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1 The Hague - Local Division UPC_CFI_620/2025 UPC_CFI_1509/2025 UPC_CFI_1511/2025 Decision of the Court of First Instance of the Unified Patent Court delivered on 10 November 2026 HEADNOTES 1. Patent on liposomes for RNA vaccine delivery held (mostly) valid and infringed. 2. The claimed range of pKa 5.0-6.8 is not to be interpreted as containing rigid cut-off limits in the present case. The claim, which includes a specific measurement method, should be read together with the description which contains a reference to a measurement imprecision for this method of +-0.2 pKa units. 3. The patent is entitled to partial priorities. The patent may rely on P1 (US830) for the range of pKa 5.0-6.7 (so partially according to G1/15), with date 6 July 2010 and for the claim with upper pKa limit 6.8 on P ...